Larry the Lizard:
My favorite way to fish these is a Texas rig. Why? Its fast, easy, and you can really work these baits in all kinds of cover effectively.
I go to Texas rig all year long, especially in coves, around heavy cover and trees. It works very well on docks and hard to get to spots, where you just know a big one is sitting.
I like Carolina rigging in a little deeper water, such as 10 feet or more, off shelves, lake humps, ridges, main and secondary lake points. When you Carolina this thing, it doesn't get all the way to the bottom, but rather suspends above the bottom. This presentation and the life-like action and distress sound that comes from the rattles just kills em, big time.
Many lakes I fish have heavy moss on the bottom, or just weeds that make fishing a little harder than average. That's when putting this things on a drop shot rig can really produce large number of fish quick. The drop shot rig keeps the bait off the bottom and out of the weeds and or moss, just above it, the fish feel the vibration, come out of the heavy stuff and bag the bait. I use this a lot during post spawn, and I have never missed with it yet.
Don't over look these lizards as a swim bait. The natural swimming motion and weedless rigging makes these great for just swimming and a whole lot of catching.